PSD-95 and Learning

Professor Seth Grant highlights PSD95 as an important example of a protein associated with a neurotransmitter receptor that affects learning.

PSD95, also known as post-synaptic density 95, is very important in the history of learning research because it binds to a neurotransmitter receptor. If you lack PSD95 then you have great difficulty learning, although the receptor still works. This establishes the fact that proteins associated with neurotransmitter receptors are instrumental in the learning process.