CA1 and Spatial Memory

Professor Eric Kandel explains that the CA1 region of the hippocampus is important for representing and remembering spaces.

The hippocampus proper has three regions: Dentate gyrus, CA3, and CA1. CA1 is closer to the output region of the hippocampus and it is important for representing space in the environment, so that individual cells in the CA1 region encode for space and therefore long-term memory for space and attentional modulation of space importantly involves the CA1 region. If you produce a genetic lesion in some of the critical signaling pathways that are involved in memory storage, and do so selectively in the CA1 region, you interfere with memory storage.