Genotyping with Microarray Technologies

Doctor Anil Malhotra discusses new technologies that allow scientists to genotype large numbers of genetic polymorphisms.

There are new [microarray] technologies now available that allow us to genotype massive numbers of polymorphisms or variations within the genome at any one time. Previously, we have been limited to looking at individual genes or a limited number of polymorphisms, but these new techniques allow us to genotype [over] five hundred thousand, up to a million SNPs or polymorphisms at a single time and thus we can essentially conduct a snapshot of an entire genome at a single timepoint.